No evidence of tumorigenicity was observed in male and female mice at codeine dietary doses around 400 mg/kg/working day (somewhere around such as 45 instances the MRHD on the mg/m2 basis).
For prescriptions exactly where a measuring unit is not really furnished, a pharmacist can provide an proper calibrated measuring machine and can provide Recommendations for measuring the proper dose.
To reduced your possibility, your health care provider should have you take the smallest dose that actually works, and consider it for your shortest attainable time. See also The best way to Use section To find out more about habit.
Retail outlet at area temperature from light-weight and dampness. Will not store in the bathroom. Hold all drugs far from young children and pets.
Promethazine HCl and Codeine Phosphate Oral Alternative is indicated to the short term reduction of coughs and upper respiratory signs and symptoms connected with allergy or maybe the widespread cold in clients 18 several years of age and older.
Pregnancy Exams: Diagnostic pregnancy checks based upon immunological reactions in between HCG and anti-HCG may lead to Wrong-adverse or Untrue-constructive interpretations.
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Though antihistamines are already discovered to generate fetal mortality in rodents, the pharmacological consequences of histamine during the rodent tend not to parallel People in guy. There won't be any adequate and perfectly-managed experiments of promethazine in pregnant Women of all Promethazine codeine syrup ages.
Simply because these reactions could be described voluntarily from a inhabitants of unsure measurement, It's not often probable to reliably estimate their frequency or establish a causal romance to drug publicity.
The chance for critical breathing challenges is larger when you start this medication, or if you are taking the wrong dose or choose more of this medication than prescribed. Getting this medication with Alcoholic beverages or other medicines that can result in drowsiness or respiratory challenges may perhaps bring about pretty really serious Uncomfortable side effects, together with Loss of life. Also, other medications can have an affect on the elimination of this product from the entire body, which may have an effect on how it really works.
For anyone who is very sleepy or have difficulty waking up right after applying this medication, end having this medication and speak to your medical professional or pharmacist instantly. Your dosage could must be reduced.
This product or service may well comprise inactive components, which can result in allergic reactions or other troubles. Check with your pharmacist for more information.
Just take this medication by mouth using a glass of water. In case the medication upsets your belly, consider it with foods or milk. Keep to the Instructions on the prescription label. Never acquire a lot more than you might be advised to acquire.
The opioid antagonists, naloxone and nalmefene, are unique antidotes for respiratory despair ensuing from opioid overdose. For clinically important respiratory or circulatory melancholy secondary to codeine overdose, administer an opioid antagonist. An antagonist should not be administered from the absence of clinically important respiratory melancholy. As the length of opioid reversal is predicted for being a lot less than the length of motion of codeine in Promethazine HCl and Codeine Phosphate Oral Solution, carefully keep track of the affected individual until finally spontaneous respiration is reliably reestablished.